Outlook 2010 constantly Not Responding even in Safe Mode

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As of yesterday Outlook 2010, connected to Exchange 2003, keeps coming up Not Responding when I am trying to move about the program or open an email. I tried to restart the computer but it hung at Logging Off... I did a hard reboot and opened Outlook 2010 in safe mode. Everything worked fine for the rest of the day. Now today I am running Outlook in Safe mode and it is locking up and showing Not Responding. When I close Outlook, Windows 7 comes up Outlook is not responding and I click Close the Program. I am then unable to open outlook, just sits at Loading Profile, until I do a hard reboot, because it will not reboot, it hangs at logging off. All other programs work fine including Word and Excel 2010, this only seems to be an issue with Outlook 2010.
 
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